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Gene Expression Literature Summary
Assay
Age
In situ RNA (section)
12.5 DPC

13 matching records from 13 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Tbx2  T-box 2  
Results  Reference
1*J:272619 Aydogdu N, Rudat C, Trowe MO, Kaiser M, Ludtke TH, Taketo MM, Christoffels VM, Moon A, Kispert A, TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme. Development. 2018 Nov 26;145(23):dev171827
1J:161903 Boogerd KJ, Wong LY, Christoffels VM, Klarenbeek M, Ruijter JM, Moorman AF, Barnett P, Msx1 and Msx2 are functional interacting partners of T-box factors in the regulation of Connexin43. Cardiovasc Res. 2008 Jun 1;78(3):485-93
1*J:34541 Chapman DL, Garvey N, Hancock S, Alexiou M, Agulnik SI, Gibson-Brown JJ, Cebra-Thomas J, Bollag RJ, Silver LM, Papaioannou VE, Expression of the T-box family genes, Tbx1-Tbx5, during early mouse development. Dev Dyn. 1996 Aug;206(4):379-90
1*J:89198 Christoffels VM, Hoogaars WM, Tessari A, Clout DE, Moorman AF, Campione M, T-box transcription factor Tbx2 represses differentiation and formation of the cardiac chambers. Dev Dyn. 2004 Apr;229(4):763-70
1J:337033 Greulich F, Rudat C, Farin HF, Christoffels VM, Kispert A, Lack of Genetic Interaction between Tbx18 and Tbx2/Tbx20 in Mouse Epicardial Development. PLoS One. 2016;11(6):e0156787
1*J:332214 Kaiser M, Ludtke TH, Deuper L, Rudat C, Christoffels VM, Kispert A, Trowe MO, TBX2 specifies and maintains inner hair and supporting cell fate in the Organ of Corti. Nat Commun. 2022 Dec 9;13(1):7628
1J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189
1J:304357 Seya D, Ihara D, Shirai M, Kawamura T, Watanabe Y, Nakagawa O, A role of Hey2 transcription factor for right ventricle development through regulation of Tbx2-Mycn pathway during cardiac morphogenesis. Dev Growth Differ. 2021 Jan;63(1):82-92
1*J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75
1J:73310 Sowden JC, Holt JK, Meins M, Smith HK, Bhattacharya SS, Expression of Drosophila omb-Related T-Box Genes in the Developing Human and Mouse Neural Retina. Invest Ophthalmol Vis Sci. 2001 Dec;42(13):3095-102
1J:198684 Trowe MO, Zhao L, Weiss AC, Christoffels V, Epstein DJ, Kispert A, Inhibition of Sox2-dependent activation of Shh in the ventral diencephalon by Tbx3 is required for formation of the neurohypophysis. Development. 2013 Jun;140(11):2299-309
1J:182725 Zhao L, Zevallos SE, Rizzoti K, Jeong Y, Lovell-Badge R, Epstein DJ, Disruption of SoxB1-dependent Sonic hedgehog expression in the hypothalamus causes septo-optic dysplasia. Dev Cell. 2012 Mar 13;22(3):585-96
1J:154920 Zirzow S, Ludtke TH, Brons JF, Petry M, Christoffels VM, Kispert A, Expression and requirement of T-box transcription factors Tbx2 and Tbx3 during secondary palate development in the mouse. Dev Biol. 2009 Dec 15;336(2):145-55

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory